My 15-inch, Mid 2009 MacBook Pro runs out of space on it's primary SSD drive from time to time. A good tool to analyse and find the resource hog is Disk Inventory X.
curl -s https://gist.github.com/estahn/6808707/raw/2663d9f2049cd114e83255187180767d7b711810/remove_old_chrome_versions.sh | sh
Open your terminal and paste this line into it. Issue solved.If you prefer a more long term solution you could run the script as a cronjob or create a rule in Hazel. Open your terminal and run:
Your Finder will open and you can drag&drop the "Versions" folder into Hazel.
open /Applications/Google\ Chrome.app/Contents
Then create a new rule. This rule will keep the last N versions (2 in this case) and will move all others into the trash.